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Query Ensembl genome database REST API for 250+ species. Gene lookups, sequence retrieval, variant analysis, comparative genomics, orthologs, VEP predictions, for genomic research.

Create Railway projects, services, and databases with proper configuration. Use when user says "setup", "deploy to railway", "initialize", "create project", "create service", or wants to deploy from GitHub. Handles initial setup AND adding services to existing projects. For databases, use railway-railway-database skill instead.

UMAP dimensionality reduction. Fast nonlinear manifold learning for 2D/3D visualization, clustering preprocessing (HDBSCAN), supervised/parametric UMAP, for high-dimensional data.

Query and analyze scholarly literature using the OpenAlex database. This skill should be used when searching for academic papers, analyzing research trends, finding works by authors or institutions, tracking citations, discovering open access publications, or conducting bibliometric analysis across 240M+ scholarly works. Use for literature searches, research output analysis, citation analysis, and academic database queries.

This skill should be used when the user asks to "create an agent", "add an agent", "write a subagent", "agent frontmatter", "when to use description", "agent examples", "agent tools", "agent colors", "autonomous agent", or needs guidance on agent structure, system prompts, triggering conditions, or agent development best practices for Claude Code plugins.

Constraint-based metabolic modeling (COBRA). FBA, FVA, gene knockouts, flux sampling, SBML models, for systems biology and metabolic engineering analysis.

GGUF format and llama.cpp quantization for efficient CPU/GPU inference. Use when deploying models on consumer hardware, Apple Silicon, or when needing flexible quantization from 2-8 bit without GPU requirements.

Expert guidance for Fully Sharded Data Parallel training with PyTorch FSDP - parameter sharding, mixed precision, CPU offloading, FSDP2

Write comprehensive clinical reports including case reports (CARE guidelines), diagnostic reports (radiology/pathology/lab), clinical trial reports (ICH-E3, SAE, CSR), and patient documentation (SOAP, H&P, discharge summaries). Full support with templates, regulatory compliance (HIPAA, FDA, ICH-GCP), and validation tools.

Parse FCS (Flow Cytometry Standard) files v2.0-3.1. Extract events as NumPy arrays, read metadata/channels, convert to CSV/DataFrame, for flow cytometry data preprocessing.

Differential gene expression analysis (Python DESeq2). Identify DE genes from bulk RNA-seq counts, Wald tests, FDR correction, volcano/MA plots, for RNA-seq analysis.

Expert in building voice AI applications - from real-time voice agents to voice-enabled apps. Covers OpenAI Realtime API, Vapi for voice agents, Deepgram for transcription, ElevenLabs for synthesis, LiveKit for real-time infrastructure, and WebRTC fundamentals. Knows how to build low-latency, production-ready voice experiences. Use when: voice ai, voice agent, speech to text, text to speech, realtime voice.

Frontend development patterns for React, Next.js, state management, performance optimization, and UI best practices.

Analyzes Move language packages against the official Move Book Code Quality Checklist. Use this skill when reviewing Move code, checking Move 2024 Edition compliance, or analyzing Move packages for best practices. Activates automatically when working with .move files or Move.toml manifests.

Comprehensive assistance with postgresql development, generated from official documentation.

Microsoft Teams bots and AI agents - Claude/OpenAI, Adaptive Cards, Graph API

Express/Hono with Supabase and Drizzle ORM

Reddit Ads API - campaigns, targeting, conversions, agentic optimization

WooCommerce REST API - products, orders, customers, webhooks

FastAPI with Supabase and SQLAlchemy/SQLModel