| 1 | Title | Title | The diagnosis or intervention of primary focus followed by the words "case report" |
| 2 | Key words | Title page | 2-5 key words identifying diagnoses or interventions, including "case report" |
| 3a | Abstract — Introduction | Abstract | What is unique about this case and what does it add to the literature? |
| 3b | Abstract — Findings | Abstract | Patient's main concerns and important clinical findings |
| 3c | Abstract — Diagnoses/Interventions | Abstract | Main diagnoses, therapeutic interventions, and outcomes |
| 3d | Abstract — Conclusion | Abstract | Main "take-away" lessons from this case |
| 4 | Introduction | Introduction | Briefly summarise and cite similar previously published cases; state why this case is unique |
| 5 | Patient information | Case presentation | De-identified demographics, main concerns/symptoms, medical/family/psychosocial history (diet, lifestyle, genetics when possible), relevant past interventions with outcomes |
| 6 | Clinical findings | Case presentation | Relevant physical examination findings and significant clinical findings |
| 7 | Timeline | Case presentation | Important dates and times as a figure, table, or narrative (historical and current episode) |
| 8a | Diagnostic assessment — Methods | Case presentation | Diagnostic methods (PE, lab, imaging, questionnaires) |
| 8b | Diagnostic assessment — Challenges | Case presentation | Diagnostic challenges (financial, language/cultural, etc.) |
| 8c | Diagnostic assessment — Reasoning | Case presentation | Diagnostic reasoning including other diagnoses considered (differential diagnosis) |
| 8d | Diagnostic assessment — Prognosis | Case presentation | Prognostic characteristics (e.g., staging) where applicable |
| 9a | Therapeutic intervention — Types | Case presentation | Types of intervention (pharmacologic, surgical, preventive, self-care) |
| 9b | Therapeutic intervention — Administration | Case presentation | Administration details (dosage, strength, duration) |
| 9c | Therapeutic intervention — Changes | Case presentation | Changes in interventions with rationale |
| 10a | Follow-up and outcomes — Assessment | Results | Clinician-assessed and patient-assessed outcomes |
| 10b | Follow-up and outcomes — Tests | Results | Important follow-up test results (positive or negative) |
| 10c | Follow-up and outcomes — Adherence | Results | Intervention adherence and tolerability (how assessed) |
| 10d | Follow-up and outcomes — Adverse events | Results | Adverse and unanticipated events |
| 11a | Discussion — Strengths/limitations | Discussion | Strengths and limitations in the management of this case |
| 11b | Discussion — Literature | Discussion | Relevant medical literature with references |
| 11c | Discussion — Rationale | Discussion | Rationale for conclusions (assessment of possible causes) |
| 11d | Discussion — Take-away | Discussion | Primary "take-away" lessons (without overgeneralizing), in a single paragraph |
| 12 | Patient perspective | Discussion | Patient shares their perspective or experience (when possible) |
| 13 | Informed consent | Other | Patient provided informed consent |