askill
jimmc414

jimmc414

Publisher on askill

8.1k total stars
Skills54
Updated 3/15/2026
GitHub
pydeseq2
pydeseq2
jimmc4142/9/2026

Differential gene expression analysis (Python DESeq2). Identify DE genes from bulk RNA-seq counts, Wald tests, FDR correction, volcano/MA plots, for RNA-seq analysis.

432
AI 92
esm
esm
jimmc4142/9/2026

Comprehensive toolkit for protein language models including ESM3 (generative multimodal protein design across sequence, structure, and function) and ESM C (efficient protein embeddings and representat...

432
AI 90
neurokit2
neurokit2
jimmc4142/9/2026

Comprehensive biosignal processing toolkit for analyzing physiological data including ECG, EEG, EDA, RSP, PPG, EMG, and EOG signals. Use this skill when processing cardiovascular signals, brain activi...

432
AI 88
perplexity-search
perplexity-search
jimmc4142/9/2026

Perform AI-powered web searches with real-time information using Perplexity models via LiteLLM and OpenRouter. This skill should be used when conducting web searches for current information, finding r...

432
markitdown
markitdown
jimmc4142/9/2026

Convert various file formats (PDF, Office documents, images, audio, web content, structured data) to Markdown optimized for LLM processing. Use when converting documents to markdown, extracting text f...

426
AI 88
vaex
vaex
jimmc4142/9/2026

Use this skill for processing and analyzing large tabular datasets (billions of rows) that exceed available RAM. Vaex excels at out-of-core DataFrame operations, lazy evaluation, fast aggregations, ef...

426
datacommons-client
datacommons-client
jimmc4142/9/2026

Work with Data Commons, a platform providing programmatic access to public statistical data from global sources. Use this skill when working with demographic data, economic indicators, health statisti...

426
matplotlib
matplotlib
jimmc4142/9/2026

Foundational plotting library. Create line plots, scatter, bar, histograms, heatmaps, 3D, subplots, export PNG/PDF/SVG, for scientific visualization and publication figures.

426
AI 93
drugbank-database
drugbank-database
jimmc4142/9/2026

Access and analyze comprehensive drug information from the DrugBank database including drug properties, interactions, targets, pathways, chemical structures, and pharmacology data. This skill should b...

426
AI 86
rdkit
rdkit
jimmc4142/9/2026

Cheminformatics toolkit for fine-grained molecular control. SMILES/SDF parsing, descriptors (MW, LogP, TPSA), fingerprints, substructure search, 2D/3D generation, similarity, reactions. For standard w...

426
AI 78
datamol
datamol
jimmc4142/9/2026

Pythonic wrapper around RDKit with simplified interface and sensible defaults. Preferred for standard drug discovery: SMILES parsing, standardization, descriptors, fingerprints, clustering, 3D conform...

426
histolab
histolab
jimmc4142/9/2026

Digital pathology image processing toolkit for whole slide images (WSI). Use this skill when working with histopathology slides, processing H&E or IHC stained tissue images, extracting tiles from giga...

426
pysam
pysam
jimmc4142/9/2026

Genomic file toolkit. Read/write SAM/BAM/CRAM alignments, VCF/BCF variants, FASTA/FASTQ sequences, extract regions, calculate coverage, for NGS data processing pipelines.

426
seaborn
seaborn
jimmc4142/9/2026

Statistical visualization. Scatter, box, violin, heatmaps, pair plots, regression, correlation matrices, KDE, faceted plots, for exploratory analysis and publication figures.

426
reactome-database
reactome-database
jimmc4142/7/2026

Query Reactome REST API for pathway analysis, enrichment, gene-pathway mapping, disease pathways, molecular interactions, expression analysis, for systems biology studies.

420
AI 95
pylabrobot
pylabrobot
jimmc4142/7/2026

Laboratory automation toolkit for controlling liquid handlers, plate readers, pumps, heater shakers, incubators, centrifuges, and analytical equipment. Use this skill when automating laboratory workfl...

420
AI 92
pyopenms
pyopenms
jimmc4142/7/2026

Python interface to OpenMS for mass spectrometry data analysis. Use for LC-MS/MS proteomics and metabolomics workflows including file handling (mzML, mzXML, mzTab, FASTA, pepXML, protXML, mzIdentML),...

420
AI 88
peer-review
peer-review
jimmc4141/26/2026

Systematic peer review toolkit. Evaluate methodology, statistics, design, reproducibility, ethics, figure integrity, reporting standards, for manuscript and grant review across disciplines.

419
AI 92

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